Use of Suppression Subtractive Hybridization for Differential Gene Expression in Stroke
نویسندگان
چکیده
منابع مشابه
Use of suppression subtractive hybridization for differential gene expression in stroke: discovery of CD44 gene expression and localization in permanent focal stroke in rats.
BACKGROUND AND PURPOSE CD44 is a transmembrane glycoprotein involved in endothelial cell recognition, lymphocyte trafficking, and regulation of cytokine gene expression in inflammatory diseases. The present report describes the discovery of upregulated CD44 gene expression and its spatial and temporal distribution in the brain after focal stroke. METHODS Rats were subjected to permanent occlu...
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The genetic background of hepatocellular carcinoma (HCC) has yet to be completely understood. Here, we describe the application of suppression subtractive hybridization (SSH) coupled with cDNA microarray analysis for the isolation and identification of differential expression of genes in HCC. Twenty-six known genes were validated as up-regulated and 19 known genes as down-regulated in HCC. The ...
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ژورنال
عنوان ژورنال: Stroke
سال: 2001
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.32.4.1020